A shipwrecked sailor stumbles upon a mysterious island and is shocked to discover that a brilliant scientist and his lab assistant have found a way to combine human and animal DNA—with horrific results.
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| Writing | H.G. Wells | Novel |
| Directing | John Frankenheimer | Director |
| Writing | Richard Stanley | Screenplay |
| Costume & Make-Up | Gary Archer | Prosthetics |
| Writing | Ron Hutchinson | Screenplay |
| Production | Tim Zinnemann | Executive Producer |
| Production | Valerie McCaffrey | Casting |
| Art | Ian Gracie | Art Direction |
| Production | Edward R. Pressman | Producer |
| Editing | Adam P. Scott | Editor |
| Sound | Gary Chang | Original Music Composer |
| Production | Claire Rudnick Polstein | Executive Producer |
| Camera | William A. Fraker | Director of Photography |
| Art | Graham 'Grace' Walker | Production Design |
| Editing | Paul Rubell | Editor |
| Art | Beverley Dunn | Set Decoration |
| Art | Lesley Crawford | Set Decoration |
| Production | James McTeigue | Production Assistant |
| Costume & Make-Up | Norma Moriceau | Costume Design |
| Editing | Thom Noble | Editor |
| Camera | Peter Sorel | Set Photographer |
| Directing | James Sbardellati | First Assistant Director |
| Camera | Ian Bird | Best Boy Grip |
| Visual Effects | Kevin Scott Mack | Visual Effects Supervisor |
| Sound | David Lee | Sound Recordist |
| Directing | Richard Stanley | Director |
| Crew | Norm Keesing | Stand In |
| Costume & Make-Up | Lance Anderson | Key Makeup Artist |
| Costume & Make-Up | Jason Baird | Makeup Artist |
| Costume & Make-Up | John M. Elliott Jr. | Makeup Artist |
| Costume & Make-Up | Bruce Spaulding Fuller | Makeup Supervisor |
| Costume & Make-Up | Leonard Engelman | Makeup Artist |
| Costume & Make-Up | Maggie Fung | Special Effects Makeup Artist |
| Costume & Make-Up | Nikki Gooley | Makeup Artist |
| Costume & Make-Up | Robert Hall | Key Makeup Artist |
| Costume & Make-Up | Paul Katte | Makeup Artist |
| Costume & Make-Up | Rolf John Keppler | Makeup Artist |
| Costume & Make-Up | Barry R. Koper | Makeup Artist |
| Costume & Make-Up | Shane Mahan | Special Effects Makeup Artist |
| Costume & Make-Up | Vera Mitchell | Hairstylist |
| Costume & Make-Up | Bill Myer | Special Effects Makeup Artist |
| Costume & Make-Up | Trish Newton | Hairstylist |
| Costume & Make-Up | Nick Nicolaou | Makeup Artist |
| Costume & Make-Up | Phil Rhodes | Makeup Artist |
| Costume & Make-Up | Mike Smithson | Makeup Supervisor |
| Costume & Make-Up | Lynn Wheeler | Key Hair Stylist |
| Production | Wil Milne | Unit Manager |
| Production | Deborah Moore | Executive In Charge Of Production |
| Production | Joe Fineman | Executive In Charge Of Post Production |
| Crew | Claire O'Brien | Post Production Supervisor |
| Production | Tony Winley | Unit Production Manager |
| Production | Ted Zachary | Executive In Charge Of Production |
| Directing | Michael Z. Hanan | Second Unit Director |
| Directing | Jane Griffin | Second Assistant Director |
| Directing | Sophie Fabbri-Jackson | Script Supervisor |
| Art | Graham Humphreys | Storyboard Artist |
| Art | Hugh 'Lewis' Dickson | Construction Foreman |
| Production | Oliver Dickson | Production Assistant |
| Camera | Jack Wareham | Assistant Camera |
| Directing | Michael Mercurio | Second Second Assistant Director |
| Directing | Toby Pease | Second Unit First Assistant Director |
| Directing | Iain Pirret | Second Second Assistant Director |
| Directing | Andrew Power | Third Assistant Director |
| Directing | Rob Visser | Second Assistant Director |
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