A medical examiner discovers that an innocent shooting victim in a robbery died of bubonic plague. With only 48 hours to find the killer, who is now a ticking time bomb threatening the entire city, a grisly manhunt through the seamy underworld of the New Orleans Waterfront is underway.
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| Writing | Daniel Fuchs | Adaptation |
| Writing | Edna Anhalt | Story |
| Directing | Elia Kazan | Director |
| Writing | Edward Anhalt | Story |
| Writing | Richard Murphy | Screenplay |
| Sound | Alfred Newman | Original Music Composer |
| Camera | Joseph MacDonald | Director of Photography |
| Production | Sol C. Siegel | Producer |
| Editing | Harmon Jones | Editor |
| Costume & Make-Up | Travilla | Costume Design |
| Sound | W.D. Flick | Sound |
| Costume & Make-Up | Charles LeMaire | Wardrobe Designer |
| Art | Lyle R. Wheeler | Art Direction |
| Sound | Roger Heman Sr. | Sound |
| Art | Thomas Little | Set Decoration |
| Art | Maurice Ransford | Art Direction |
| Costume & Make-Up | Ben Nye | Makeup Artist |
| Art | Fred J. Rode | Set Decoration |
| Directing | F.E. 'Johnny' Johnston | Assistant Director |
| Crew | Michael Audley | Dialogue Coach |
| Sound | Bernard Mayers | Orchestrator |
| Sound | Red Nichols | Orchestrator |
| Sound | Alfred Newman | Conductor |
| Costume & Make-Up | Charles LeMaire | Wardrobe Coordinator |
| Production | Joseph C. Behm | Production Manager |
| Crew | Lyman Hallowell | Editorial Staff |
| Sound | Benny Carter | Orchestrator |
| Directing | Stanley K. Scheuer | Script Supervisor |
| Costume & Make-Up | Sam Benson | Wardrobe Master |
| Sound | Ernie Felice | Orchestrator |
| Sound | Herbert W. Spencer | Orchestrator |
| Sound | Edward B. Powell | Orchestrator |
| Camera | Til Gabani | Camera Operator |
| Crew | Jack N. Young | Stunts |
| Visual Effects | Fred Sersen | Visual Effects |
| Writing | John Lee Mahin | Writer |
| Writing | Philip Yordan | Writer |
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