UFC on ESPN 68: Gamrot vs. Klein was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on May 31, 2025, at the UFC Apex in Enterprise, Nevada, part of the Las Vegas Valley, United States. A women's flyweight bout between Erin Blanchfield and Maycee Barber was originally scheduled to headline the event. However, minutes before their walkouts were to take place, Barber had to withdraw due to a medical issue involving a seizure. Therefore, a lightweight bout between former KSW Featherweight and Lightweight Champion Mateusz Gamrot and Ľudovít Klein inadvertently headlined the event.

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